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please click on here....Neurologic and eye disease
Neurologic symptoms are the most common vaccine reaction seen in
dogs. Canine distemper vaccination is the most common cause of
neurologic disease, and can cause an inflammation of the brain.
Measles vaccine in puppies has been reported to rarely cause damage
to the nervous system. Cerebellar disease has been reported in
puppies less than 5 weeks of age who were vaccinated with a modified
live vaccine. Canine adenovirus-1 is known to cause an allergic
uveitis (inflammation of the eye), often called 'blue eye.' Most
vaccines now contain canine adenovirus-2 instead of adenovirus-1,
almost eliminating the chance of blue eye occurring today.
Discomfort and swelling at the
Pain, swelling, redness, and irritation can occur at the injection
site. These effects generally occur within 30 minutes to 1 week of
the vaccination. If the signs persist, or are severe, contact your
veterinarian. Occasionally, abscesses can form at the injection
site. These abscesses are generally not caused by infection, but by
the body's over-reaction to the vaccine.
Mild fever, decreased appetite and
Mild fever, decreased appetite, and depression may be observed for
1-2 days following vaccination, most commonly when modified live
vaccines are used. Generally, no treatment is warranted. Severe
illness can occur if vaccines designed for intranasal use are
accidentally injected. Severe reactions can also occur if any of a
vaccine made for injection accidentally enters an animal's eyes,
nose, or mouth.
Respiratory signs after intranasal
Dogs vaccinated with the intranasal Bordetella and/or parainfluenza
vaccine may develop a mild cough, which generally does not require
treatment. They may spread the vaccine-form of the virus to other
animals through their coughing.
Rarely, lameness can result from several different vaccinations.
They may develop an immune-mediated arthritis in one or more joints,
which is often progressive and relapses commonly occur. Dogs with
this immune disorder generally have short life spans due to other
complications. Hypertrophic osteodystrophy: some large-breed dogs may
develop hypertrophic osteodystrophy following canine distemper
vaccinations given between 2 and 5 months of age. They may also
develop respiratory signs, enlarged lymph nodes, and diarrhea. The
hypertrophic osteodystrophy is treated with glucocorticoids and the
signs of the disease usually resolve.
Shedding of vaccine agent
Vaccine virus may be found in the nasal secretions of dogs
vaccinated intranasally. In addition, vaccine parvovirus is shed in
the feces of vaccinated dogs, canine adenovirus-1 can be shed in the
urine, and canine adenovirus-2 can be found in nasal secretions.
These viruses are the vaccine forms of the virus; they do NOT revert
back to the disease-causing strains.
Birth defects or infections
The vaccination of pregnant animals with a modified live vaccine can
result in birth defects or abortions. It is recommended that
modified live vaccines NEVER be given to pregnant animals. In
addition, vaccinating puppies less than 4-5 weeks of age, can
actually result in them becoming infected and developing disease
from modified live vaccines....to
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